I see that the NVDA screen reader cannot read the icon menus that start from the top on the left hand side of the QtCreator main window. I guess this is the problem you have seen with QtCreator? That left most panel is called the Mode Selector and you can close it if is too noisy for your screen reader.
Maybe you could ask the QtCreator developers to make that panel more accessible to screen readers?
On the whole though it looks like most of the menus should work with a screen reader (I tried it with NVDA but did not test every menu though).