Well you start by not using the Designer because you are going to want to have complete control of all the objects this is going to use. Next you learn how to code in pyqt using its native Layout elements along with the various buttons. The vertical sliders are not overly difficult but those on/off buttons over the vertical sliders might require specialized implementation as you may have to make your own. The LineEdit boxes and Labels are no issue either. But yes this could ALL be implemented by using pyqt. However that means diving into many many elements of pyqt to answer properly or give you the fish and then you miss out on the fun of catching (designing and making) your own fish (view).
However I am running a Python/PyQt Discord message server where this kind of one-on-one help can be obtained for the same cost of posting a question on this forum ;) (aka free) just drop me a PM or post an email and I will send you an invite. But be prepared to learn how to fish ;)