Hey, my dev is pyqt on Mac... tooling around the internet I found that there is a brew install python option that force-includes pyqt... but I seem to have lost the link.
That said, when it comes to python/node, I'm a fan of local environments and minimal brew usage. I downloaded Qt/sip/pyqt src and built everything inside a python venv and found it to be really easy.
Just recently I hammered out the details so that I could get designer custom widgets working and logged my steps here:
hopefully this helps,