I have the same issues about two days now, I had clean the registry, also all qt settings on other locations that isn't the drive c qt installation, uninstall qt, I did this many times and I also have a working qt install on another computer which I exchange the install qt folder and in my problem computer it won't work and the qt installation folder works on another computer, system oaths is the same, so I came down to operating system issues, I use dependency walker to see what uic.exe requires and in my computer about 4 ot 5 dll it calls and the other computer It call a number of windows kit dll, installing the kit disnt help, I am currently running windows repairs well I will update you guys of my findings