@BigBen
This sounds like you would be best looking for openCV's VideoCapture.open() questions? Maybe whatever it does requires certain files in certain places which are not present/found on the other system, either openCV runtime files or the file you are trying to open?

@JonB Thanks Jon. I will look into those suggestions. I think at this point though, the best thing for me to try, rather than thrashing around with my current project, would be for me to start a new project focused on just replicating this specific issue. I'll try and pare this down to minimal required code, just enough to reproduce the problem This will make findings clearer and easier to communicate to others. If I get to a point where I have something useful to share, I'll do so. Thank you again..Mark