QserialPort Frame Burts / time efficiency

[Flaming Moe]

Hello there,

i´m new to serial communication on OS driven Platforms and have a question regarding efficency of Portusage.

Let´s assume the following Szenario:
I have a Qt project where are existing several instances of Class. These classes are kind of mirrors of physical existing devices which are connected in a bus through a USB<=>Uart Bridge.

There are two ways possible to do the communication.
1.) Send a Frame in a Byteburst for each Instance-PhysicalDevice Pair (calling serial.write severall times)

2.) Gather all Frames and send them in one large frame (calling serial.write just once)

I´m talking about ~20 Instance-PhysicPairs.
Is one large frame "MUCH" more efficient or just "a little" more efficient than multiple bursts?

best regards,
Moe